Tapentadol for Moderate to Severe Pain Relief is manufactured by Unimark Remedies Limited. Unimark Remedies Limited is an ISO 14001 and 18001 certified company that manufactures pharmacueticals like cephalosporins, carbapenems, antibacterials and antimicrobials. Tapentadol for Moderate to Severe Pain Relief is in a class of medications called opiate [narcotic] analgesics. It works by changing the way the body responds to pain. Tapentadol is used to treat moderate to severe pain that is expected to last for a short Time. It comes in a tablet form. Tapentadol is a centrally-acting analgesic with a dual mode of action as an agonist at the µ-opioid receptor and as a norepinephrine reuptake inhibitor. It has opioid and nonopioid activity in a single compound.